• Clinical science

Congenital anomalies of the kidneys

Summary

Congenital anomalies of the kidneys and urinary tract (CAKUT) are one of the most common malformations diagnosed in newborns. The pathogenesis of CAKUT is multifactorial; both specific genes and environmental factors (e.g., in utero exposure to ACE inhibitors) have been implicated in the development of CAKUT. Even though most cases are initially asymptomatic, up to 50% of children with end-stage renal disease have an underlying CAKUT. For this reason, early identification of these malformations is essential in order to prevent renal damage.

Overview

Anomalies of the collecting system

Malformation of the renal parenchyma

Renal dysgenesis

Congenital solitary kidney

Anomalies of kidney migration

Etiology

References:[1]

Clinical features

References:[1]

Diagnostics

References:[2]

Differential diagnoses

Floating kidney

References:[3]

The differential diagnoses listed here are not exhaustive.

Treatment