Not all AI belongs in clinical care. LiSA does.

Meet LiSA, our practice-focused AI search agent specifically designed to direct you to relevant information in every moment of care. Built by clinicians, for clinicians.

Request Exclusive Access

Not all AI belongs in clinical care. LiSA does.

Meet LiSA, our practice-focused AI search agent specifically designed to direct you to relevant information in every moment of care. Built by clinicians, for clinicians.

Request exclusive access
Your data will be processed to provide early access (Art. 6(1)(f) GDPR).
Our Privacy Policy applies.

Thank you for signing up!

We’re reviewing requests and granting access in limited phases, starting with AMBOSS members in the U.S.

As soon as your spot opens up, we'll let you know.

Something went wrong while submitting the form.
AI Search Agent

Clinical guidance wherever you go

Designed to fit seamlessly into your clinical workflow

Clinical Focus

Finally, AI designed with clinicians in mind.

Request exclusive access
Request Exclusive Access

Built by your peers

LiSA is developed by clinicians, not engineers guessing how you work. That’s why every detail is designed around your needs, from what LiSA shows to how she shows it.

Evidence-based and practice-focused

LiSA draws exclusively on selected external sources, including clinical US guidelines, a comprehensive drug database, and the curated AMBOSS knowledge base: only relevant clinical information from trusted sources that you can trace, designed to support informed decision-making.

Designed for clinical care

Clinical care is more than answering individual questions. It’s about understanding the broader context, planning ahead, and facing individual challenges. LiSA guides you every step of the pathway to all the sources you need, without replacing your judgment.

Structure

Every detail designed for clarity

Seamlessly connected

LiSA provides a unique combination of flexible AI interaction and access to AMBOSS’s trusted medical knowledge, distilled from the latest evidence and refined through human expertise, critical evaluation, and clinical consensus.

Anticipatory deep dives

LiSA anticipates your needs, presenting further evidence so you can see the broader context and consider aspects beyond your initial clinical question.

Personalized to your specialty

LiSA adapts to your specialty, recognizing that each discipline needs different information for the same clinical scenario.

Differing recommendations

LiSA highlights when sources contain differing recommendations, so you can compare every nuance of evidence at a glance.

Detailed inline citations

LiSA links directly to the original sources, which you can review and verify, supporting confident and defendable decisions.

Transparent limits

If LiSA cannot find relevant information for your question, she is trained to tell you. No guessing. No false confidence.

Johanna Hase, M.D.

Editor-in-Chief and Director of Medical

"Our incredible team of clinicians and engineers built LiSA because we know that existing tools miss what really matters in clinical care: clarity and relevance. Other tools either draw from unverified sources or overwhelm you with study results, leaving you to bridge the gap between research and clinical care. LiSA is special because she combines our trusted AMBOSS knowledge base with a hand-curated selection of the most important evidence-based resources for clinical care."
Use Cases

Where LiSA fits into your day

Ask LiSA your toughest clinical questions, and turn them into confident decisions.

Explore different types of queries: diagnoses, treatment options, drug interactions, and US guideline updates.

Consult LiSA for a quick second opinion to make sure you’re not missing the latest clinical evidence.

Request Exclusive Access

We’re introducing LiSA in stages, beginning exclusively with active AMBOSS members in the US.

Request exclusive access
Request exclusive access
Your data will be processed to provide early access (Art. 6(1)(f) GDPR).
Our Privacy Policy applies.

Thank you for signing up!

We’re reviewing requests and granting access in limited phases, starting with AMBOSS members in the U.S.

As soon as your spot opens up, we'll let you know.

Something went wrong while submitting the form.
FAQs

Everything you need to know about LiSA

Who gets early access to LiSA, and why is it limited?

We’re launching LiSA in phases, beginning exclusively with active AMBOSS members in the US. This phased rollout ensures our most engaged clinicians experience LiSA first and benefit from her clinical guidance before we expand access more broadly.

What if I want to recommend LiSA to friends or colleagues?

We love that you want to share your enthusiasm for LiSA. Your peers can request access via this page and will be notified as soon as we can grant it. Please note that an active AMBOSS membership is required.

What makes LiSA unique?

LiSA connects natural-language questions to curated, clinically validated sources, including the AMBOSS Knowledge base, selected US guidelines, and drug information. She helps clinicians efficiently identify and access relevant, traceable evidence. This approach combines the flexibility of AI search with the reliability of trusted medical content, supporting confident, evidence-based decision-making on the go.

How do you ensure the highest clinical relevance?

Clinical relevance is at the core of LiSA. Our team includes experienced clinicians who bring their day-to-day expertise directly into product design. LiSA is grounded in a peer-curated selection of trusted, clinically relevant sources. For us, quality matters not only in the information provided but also how it is presented: LiSA directs you to the most relevant clinical evidence in a clear, structured format that fits effortlessly into your workflow, streamlining the path from search to confident decision-making.

What is LiSA's output based on?

LiSA draws on a peer-curated selection of clinical sources, including external US guidelines, a comprehensive drug database, and the trusted AMBOSS knowledge base. Based on this selective approach, LiSA directs you to evidence that is relevant, current, and aligned with the highest clinical standards.

Does LiSA hallucinate? What happens if she doesn't know the answer?

LiSA draws on trusted medical sources, which greatly reduces the risk of hallucinations: plausible-sounding but incorrect information. If LiSA cannot find relevant information for your question, she is trained to indicate this. However, as with any AI system, there are limitations. Even with high-quality sources, LiSA may miss or misinterpret details. That’s why LiSA’s output should always be used as support, not as a replacement for professional medical judgment. 

How does LiSA deal with differing recommendations?

When sources contain differing recommendations, LiSA is trained to highlight these differences transparently, allowing you to compare perspectives and make a well-informed decision.

How does LiSA tailor her clinical guidance to my needs?

LiSA is designed to integrate seamlessly into clinical workflows. Your specialization is taken into account, recognizing that each discipline may require different information for the same clinical scenario. 

Does LiSA support other languages?

Yes, LiSA is trained to provide responses in the same language as the question is submitted.

What is LiSA's eco footprint?

LiSA's focus on processing only the most relevant clinical sources means that computational demands, energy consumption, processing time, and carbon footprint are kept to a minimum, while improving the quality of the output by eliminating nonclinical information.