Abbreviation: AHTR
An adverse reaction to blood transfusion that occurs within the first 24 hours after transfusion. Causes include ABO incompatibility and the immune response to other blood group antigens (e.g., Kell, Duffy, Jk). Results in the destruction of donor red blood cells by recipient antibodies. Manifestations include fever, gastrointestinal symptoms, and allergic symptoms (e.g., flushing, itching, urticaria). Can cause disseminated intravascular coagulation, renal failure, and jaundice.