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Virtual histopathology slide box

Last updated: September 21, 2021

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The virtual histopathology slide box provides an introduction to the histology of diseased cells and tissues. Each specimen is accompanied by a caption that provides information on staining, magnification, and the structures shown. Virtual microscopy is provided in cooperation with Smart Zoom®. Complementary to this article, the virtual histology slide box contains numerous images of captioned normal histological specimens with the same virtual microscopy feature. Some images from that article have been included here also for easy comparison.


Capillary hemangioma

Basal cell carcinoma

Cutaneous squamous cell carcinoma


Inflammatory diseases of cutaneous and subcutaneous diseases

Gout tophus

Pilonidal cyst

Normal tissue for comparison

Atherosclerosis of the coronary artery

Normal tissue for comparison

Stages of myocardial infarction

Normal tissue for comparison

Infective endocarditis

Normal tissue for comparison

Pulmonary alveolar edema



Lobar pneumonia

Pulmonary sarcoidosis

Pulmonary tuberculosis

Pulmonary aspergillosis


Non-small-cell-lung cancer

Squamous cell carcinoma

Adenocarcinoma of the lung

Small cell lung cancer

Normal tissue for comparison

Barrett esophagus

Barrett esophagus

Barrett esophagus with adenocarcinoma

Normal tissue for comparison


Type B gastritis: Helicobacter pylori

Foveolar hyperplasia

Normal tissue for comparison

Infarction of small intestine with ischemia (mesenteric infarction)



Celiac disease


Enterobius vermicularis

Crohn disease

Ulcerative colitis

Pseudomembranous colitis


Colonic lipoma


Normal tissue for comparison


Chronic hepatitis B

Cirrhosis of the liver


Hepatocellular Carcinoma

Normal tissue for comparison

Adenocarcinoma of the gallbladder

Normal tissue for comparison

Pancreatic ductal adenocarcinoma

Normal tissue for comparison

Cancer in situ

Ductal carcinoma in situ

Invasive tumors

Invasive ductal carcinoma of the breast

Invasive lobular carcinoma of the breast

Benign neoplastic changes of the breast

Fibroadenoma of the breast

Fibrocystic disease of the breast

Normal tissue for comparison



Squamous cell carcinoma of the cervix

Normal tissue for comparison

Fallopian tubes

Ectopic pregnancy in the fallopian tubes

Normal tissue for comparison


Ovarian endometriosis

Ovarian tumors

Brenner tumor

Mature teratoma of the ovary

Serous cystadenocarcinoma

Normal tissue for comparison


Benign prostatic hyperplasia

Adenocarcinoma of the prostate

Normal tissue for comparison

Squamous cell carcinoma of the penis



Normal tissue for comparison


Coagulative necrosis (renal infarction)

Diabetic nephropathy

Clear cell renal cell carcinoma

Normal tissue for comparison


Urothelial carcinoma of the bladder

Normal tissue for comparison


Nodular goiter

Hyperthyroidism (Graves disease)

Thyroid cancer

Papillary thyroid carcinoma

Medullary thyroid carcinoma

Normal tissue for comparison

Adrenal gland

Adrenal adenoma


Normal tissue for comparison

The following slides are sorted by disease rather than organ systems.

Acute lymphoblastic leukemia

Acute myeloid leukemia

Chronic lymphocytic leukemia (CLL on blood smear)

Chronic myeloid leukemia (CML on blood smear)

Hodgkin lymphoma

Non-Hodgkin lymphomas

Hairy cell leukemia

Multiple myeloma

Follicular lymphoma

Mantle cell lymphoma

Diffuse large B cell lymphoma

Chronic lymphocytic leukemia (CLL)

CLL is classified as a lymphocytic lymphoma (belonging to the group of the B cell Non-Hodgkin lymphomas). However, for the sake of clarity, here it is shown in the context of other types of leukemia.

Myeloproliferative neoplasms

Essential thrombocythemia

Chronic myeloid leukemia (CML)

CML is classified as a myeloproliferative neoplasm. However, for the sake of clarity, here it is shown in the context of other types of leukemia.

This section treats blood and bone smears that show anemia and a few unspecific changes that indicate abnormal hematopoiesis and may occur in a variety of diseases. For oncological diseases of the blood, see the section on blood and lymphatic system above.

Pathological changes of erythrocytes

Basophilic stippling



Iron deficiency anemia

Hemolytic anemia

Megaloblastic anemia (KM)

Sickle cell disease


Pathological changes of leukocytes

Left shift

Infectious mononucleosis





Ewing sarcoma

Blood vessels


Aortic dissection

Giant cell arteritis

Capillary hemangioma

Normal tissue for comparison


Acoustic neuroma

Normal tissue for comparison