Last updated: August 22, 2021

Summarytoggle arrow icon

Tenosynovitis is the inflammation of a tendon (tendinitis) and its synovial sheath (synovitis). This inflammation is often due to tendon overuse (e.g., texting, typing), but can also be due to systemic diseases (e.g., rheumatoid arthritis, sarcoidosis) or infection following a penetrating injury (e.g., animal/human bites, thorn prick injury). The tendons of the hand and wrist are most commonly affected. Patients typically present with pain which is worsened by activity, edema of the affected tendons, and pain along the tendon course on stretching of the tendon. The diagnosis is established clinically but may require additional pathogen isolation for treatment planning in cases of bacterial tenosynovitis. Administration of NSAIDs and immobilization of the affected tendons is often sufficient for treating tenosynovitis. In cases of severe or persistent symptoms glucocorticoid injections into the tendon sheath are usually effective. Few cases require surgical splitting of the constricting ligaments of the affected tendons.

Etiologytoggle arrow icon

Clinical featurestoggle arrow icon

  • Tendons of fingers and wrist are commonly affected [2]
  • First sign: pain on passive extension of the affected tendon (affected fingers are slightly flexed at rest)
  • Swelling
  • Palpable crepitation
  • Fever and erythema in the case of bacterial infections
  • Late signs
    • Tenderness along the affected tendon
    • Sharp, stabbing pain worsened by activity, followed by constant dull ache at rest

Subtypes and variantstoggle arrow icon

Stenosing tenosynovitis (trigger finger) [2]

  • Epidemiology [3]
    • Sex: > (6:1)
    • Age: > 40 years
  • Etiology: usually idiopathic
  • Pathophysiology: fibrocartilaginous metaplasia of the tendon sheath of the A1 annular pulley → loss of smooth gliding of the finger flexor tendons under the annular pulley → finger gets locked in flexed position [3]
  • Clinical features [3]
    • Trigger finger: locking of a finger in flexed position which releases suddenly with a snap/pop on extension; often painful
    • Often associated with tenderness and a palpable nodule at the base of the metacarpophalangeal joint
    • Mostly affects thumbs and ring fingers
  • Diagnostics: clinical diagnosis
  • Treatment: see below

De Quervain tenosynovitis [4]

  • Description: noninflammatory thickening of the tendons of the abductor pollicis longus and extensor pollicis brevis due to myxoid degeneration
  • Epidemiology
    • Sex: >
    • Age: 30–50 years
  • Etiology
    • Repetitive/prolonged abduction and extension of the thumb: often seen in golfers and tennis players, individuals who text a lot, and young parents (due to the repeated strain of lifting the baby)
    • Inflammatory conditions such as rheumatoid arthritis
  • Clinical features
    • Pain with or without swelling of the radial styloid
    • Pain may radiate to thumb or elbow, exacerbated by movement/grasping objects.
    • Positive Finkelstein test: examiner grasps the affected thumb and exerts longitudinal traction across the palm of the hand towards the ulnar side, which causes pain
  • Diagnostics: clinical diagnosis
  • Treatment: see below

Diagnosticstoggle arrow icon

Tenosynovitis is a clinical diagnosis with specific tests used to establish the etiology.

Treatmenttoggle arrow icon

Referencestoggle arrow icon

  1. Sexton DJ. Infectious tenosynovitis. In: Post TW, ed. UpToDate. Waltham, MA: UpToDate. Last updated: August 26, 2016. Accessed: December 17, 2016.
  2. Editors of Informed Health Online. Tenosynovitis: Overview. 2018.
  3. Makkouk AH, Oetgen ME, Swigart CR, Dodds SD. Trigger finger: etiology, evaluation, and treatment. Current Reviews in Musculoskeletal Medicine. 2008; 1 (2): p.92-96.doi: 10.1007/s12178-007-9012-1 . | Open in Read by QxMD
  4. George Ray; Michael A. Tall.. Tenosynovitis. StatPearls. 2019.

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