- Clinical science
Osteoarthritis (OA) of the hip (coxarthrosis) and knee (gonarthrosis) is a disabling joint disease characterized by degeneration of the joint complex (articular cartilage, subchondral bone, and synovium). Although the exact etiology is unknown, risk factors include advanced age, joint overuse, obesity, previous injuries, and asymmetrically stressed joints (as in hip dysplasia, Perthes disease, etc.). Patients in the early phase of the disease present with joint stiffness and pain on initial movement and on constant, severe load bearing. During the later stages of the disease, excruciating pain may appear even during rest. Additionally, range of motion is drastically reduced and discrepancies in limb length, alignment, or stability appear. Diagnosis is predominantly based on clinical and radiological findings. Initial treatment includes lifestyle changes and physical measures (joint braces, occupational therapy, weight loss), and pain medication (NSAIDs). If medical interventions fail to improve the patient's quality of life, surgical procedures such as joint replacement may become necessary.
- The risk of developing hip and knee OA increases with age. The number of people affected by knee and hip OA in the USA is increasing because of a general increase in average life expectancy.
- Age: Peak incidence at initial diagnosis is 50–60 years of age.
- Sex: ♀ > ♂, especially in patients older than 50 years
Epidemiological data refers to the US, unless otherwise specified.
See also "Clinical features” in.
- Pain in the groin area and above the greater trochanter
- Increased contracture in the flexor, external rotation, and adduction position → antalgic gait
- Early signs: limited and painful internal rotation of the hip joint
- Pain on palpation: greater trochanter, groin
- Positive Thomas test
- Function: test for hip flexion contracture
- Position: supine
- Procedure: Examiner passively flexes the hip joint opposite to the affected side to a maximum to compensate lumbar lordosis.
- Positive test: If flexion contracture is present, the ipsilateral leg will simultaneously flex independently as a reflex.
- Frequent exercise, minimal load → Joint-friendly exercises are also recommended after endoprosthesis implantation (swimming and cycling).
- Weight loss may be indicated.
- Physical therapy
- Pain medication ()
- Use of a forearm-supported crutch on the healthy, unaffected side when walking
- Orthotic insoles
Indications for surgery are primarily based on the level of patient suffering.
- Total hip replacement
- Hip hemiarthroplasty
- Postoperative deep venous thrombosis prophylaxis is needed for hip replacement and any surgery to correct a fracture close to the hip joint.
- Perioperative start
- For 28– 35 days postoperatively
Unicondylar knee replacement
- Description: unicompartmental prosthesis of the femoral and tibial articular surface with insertion of a plastic sliding surface (mainly polyethylene) between both prosthetic components
- Indication: unilateral osteoarthritis of the inner and outer surface of the joint; more frequently internal in varus gonarthrosis
Bicondylar knee replacement(total knee replacement)
- Both condyles of the femur and the joint surface of the articular surface of the tibial head are replaced.
- Insertion of a plastic sliding surface (mainly polyethylene) between both prosthetic components
- If necessary, additional replacement of the posterior surface of the patella (tricondylar knee replacement)
- Indication: knee osteoarthritis, which is nonresponsive to conservative treatment and severely restricts the patient's quality of life
Patellofemoral joint replacement
- Description: prosthetic replacement of the femoral trochlear (= patella condyle) and the rear surface of the patella
- Indication: mainly isolated degenerative alterations of the femoropatellar joint
- Unicondylar knee replacement
Constrained prosthesis: rotating hinge knee prosthesis
- Indication: severe knee osteoarthritis with ligament insufficiency and femorotibial rotational malalignment
- Description: analogous to the bicondylar knee prosthesis; However, the femoral and tibial components are larger shaft prostheses that are more deeply anchored and are connected via a movable axis.
- Postoperative deep venous thrombosis prophylaxis is to be administered for knee replacement and any surgery to correct a fracture located close to the knee joint
- Perioperative start
- For 11–14 days postoperatively
Other surgical procedures
- Corrective osteotomy (valgus or varus)
- Arthrodesis: surgical fusion of the joint; very rare in osteoarthritis of the hip and knee
- Injury to surrounding structures (tendons, nerves, vessels)
- Thrombosis, embolism
- Material fracture, bone fracture
- Post-traumatic osteoarthritis
- Compartment syndrome
Special complications: soft tissue ossification / myositis ossificans (heterotopic ossification)
Short description: soft tissue and muscle ossification (= heterotopic ossification), which occurs congenitally or after tissue or joint injuries, or surgery
Localized course: (myositis ossificans localisata)
- Clinical features: restriction of movement, muscle stiffness
- Treatment: radiotherapy, possibly surgery
- Prophylactic measures against recurrence: single dose radiotherapy recommended (possibly postoperative or preoperative)
Progressive generalized disease: (myositis ossificans progressiva/fibrodysplasia ossificans progressiva)
- Etiology: extremely rare, autosomal dominant hereditary disease
- Pathophysiology: Fibrocytes produce bone tissue instead of scar tissue in all types of trauma.
- Generalized ossification mainly from cranial to caudal (life-threatening if the respiratory muscles are affected)
- Malformation of the large toes is frequently observed at birth.
- During the course of the disease, large, painful, well-vascularized swellings appear at various sites, which develop into bone tissue after regression.
- Localized course: (myositis ossificans localisata)
We list the most important complications. The selection is not exhaustive.