Summary
A fracture is a partial or complete interruption in the continuity of bone. The most common cause is trauma, followed by diseases (e.g., osteoporosis) that result in weakened bone structure. The latter results in pathologic fractures, which are fractures that would not usually occur if the bone structure was not weakened. Open fractures, in which the bone is exposed due to severe soft tissue injury, are associated with a significant risk of infection and poor wound healing. Fracture management can be conservative (e.g., cast or splint) or surgical, and generally involves anatomic reduction, fixation, and/or immobilization. Complications include acute nerve and vascular injury and compartment syndrome, as well as long-term complications such as avascular necrosis and nonunion.
Etiology
- Trauma: mechanical stress and/or loading
- Weakened bone structure: osteoporosis, bone tumors, metastasis, Paget disease
References:[1]
Classification
Fracture classification
Based on the following characteristics:
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Anatomy
- Location: affected bone (proximal, distal)
- Position: diaphysis, metaphysis, epiphysis
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Extent
- Complete
- Incomplete
- Orientation: transverse, oblique, spiral
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Displacement
- Rotated: rotation around the longitudinal axis
- Angulated: angulation of the axis
- Translated: lateral movement of the bone fragments
- Longitudinal displacement of bone fragments
- Distraction: elongation
- Impaction: shortening
- Fragmentation
-
Soft tissue involvement
- Closed fracture (simple fracture; does not come into contact with the outside environment)
- Open fracture
- Growth plate involvement (pediatric fractures): Salter-Harris fractures
Overview of common fractures
Common fractures in children
See “Pediatric fractures” for details.
Common fractures in adults
Pathologic fracture
- Definition: a spontaneous fracture following mild physical exertion or minor trauma; (e.g., lifting something, bending over, or sneezing/coughing) due to abnormal weakness of the bone that is caused by an underlying condition
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Etiology
- Disorders affecting bone metabolism
- Osteoporosis (most common cause)
- Paget disease of bone
- Osteopetrosis
- Osteomalacia
- Osteogenesis imperfecta
- Masses
- Malignant bone tumors and bone metastases
- Benign bone tumors (including bone cysts)
- Infection: chronic osteomyelitis
- Disorders affecting bone metabolism
- Common locations: spine (vertebral compression fractures), hip, wrist
Open fracture [2]
- Definition: a fracture in which the bone and/or soft tissue are exposed
- Etiology: high energy trauma
-
Clinical features
- Open wound
- Possibly comminuted bone
- Possibly deformed limb
-
Diagnostics
- Evaluation of the fracture
- Evaluation of movement and neurovascular status of all involved limbs
- Imaging
-
Management
- Surgery within 8–24 hours to stabilize the fracture (e.g., splint, brace)
- Operative therapy (depending on the type of injury): internal or external fixation
- Nonoperative therapy
- Antibiotic prophylaxis (IV)
- Tetanus prophylaxis if vaccine status is outdated or unknown
- Wound management: For further information see “Acute wound management” in “Wound treatment.”
Operative management of open fractures should not be delayed because of the high risk of wound infection.
Other fractures
- Stress fracture
- Avulsion fracture: a fracture that occurs from bone shearing at the insertion point of a tendon or ligament
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Forearm fractures
- Colles fracture: distal radius ± distal ulna
- Smith fracture: distal radius
- Monteggia fracture: proximal one-third of the ulna and dislocation of the radial head
- Galeazzi fracture: distal radial shaft and dislocation of the distal radioulnar joint
- Boxer fracture
- Scaphoid fracture
- Ankle fracture
- Midfoot fracture (Lisfranc fracture): a tarsometatarsal fracture that can involve damage to the cartilage of the midfoot joints.
- Jones fracture: fracture at the base of the shaft of the fifth metatarsal bone
- Tibial fracture
- Femoral shaft fracture
- Femoral neck fracture
- Pelvic fracture
- Vertebral fractures (including compression fractures)
Clinical features
- Pain, redness, and swelling at the site of injury
- Deformity and axis deviation
- Bone fragments penetrating the skin
- Palpable step-off or gap
- Bone crepitus
- Concomitant soft tissue injuries
- Neurovascular compromise below the site of injury
Diagnostics
Clinical assessment
- Assess for signs of a fracture and concomitant injuries
- Assess for neurovascular compromise and compartment syndrome with the 6 Ps: pain, pallor, pulselessness, paresthesia, paralysis, and poikilothermia
Imaging
-
X-ray
- Requirements
- 2 views
- 2 joints (if limb fracture)
- 2 times (prereduction and postreduction)
- Radiographic signs of a fracture include a radiolucent fracture line and cortical disruption.
- Describe fracture based on the anatomic location, alignment , angulation, and articular involvement (see “Classification” above for details)
- X-ray imaging has a low sensitivity for detecting stress fractures.
- Requirements
- CT/MRI (not routine): indicated in preoperative planning for complicated fractures, assessment of associated injuries, and inconclusive x-ray findings
Treatment
General approach
- Wound care
- Pain management (e.g., non-opioid analgesics, opioids)
-
Fracture care (conservative or surgical)
- Anatomic reduction
- Fixation
- Immobilization
Conservative fracture management
-
Indications
- Stable fractures
- Mainstay management of pediatric fractures (see “Pediatric fractures” for details)
- Procedure: closed reduction; and, if necessary, immobilization with a cast or splint of the fractured bone and adjacent joints
Surgical fracture management
-
Indications
- Open fractures
- Unstable fractures (e.g., extremity fractures, pelvic fractures)
- Severe displacements (e.g., rotational deformities) and displaced fragments
- Inadequate manual reduction and fixation
-
Procedure: anatomic reduction of the fracture and subsequent fixation and immobilization
- External fixation: immobilizing a fracture using pins or screws that are secured outside the skin
- Internal fixation: immobilizing a fracture using implants (e.g., plates, screws, wires)
- Open reduction and internal fixation: realignment of the ends of a fracture, and stabilization of the fracture using implants (e.g., plates, screws, wires)
Complications
Acute complications
- Neurologic and vascular injury (e.g., bleeding, hematoma, seroma)
- Compartment syndrome
- Wound infection, osteomyelitis
- Secondary dislocation
Long-term complications
- Avascular necrosis
- Post-traumatic osteoarthritis
- Complex regional pain syndrome
- Joint stiffness/contracture
- Joint instability
- Heterotopic ossification
- Children: growth disturbances after growth plate injury (Salter-Harris fracture)
Nonunion [3]
- Definition: incomplete healing of a fracture which results in the creation of a false joint (pseudarthrosis)
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Risk factors
- Poor vascular supply
- Insufficient immobilization
- Comorbidities (e.g., diabetes mellitus, osteoporosis)
- Open fractures
- Infection
- Smoking
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Clinical features
- Pain, swelling
- Limited weight-bearing capacity
- Reduced range of motion persisting after the normal duration of healing (usually 6–9 months)
-
Types
- Hypertrophic nonunion: callus formation in the fracture zone
- Atrophic nonunion: atrophic bone without callus formation
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Treatment
- Debridement and resection
- Osteosynthesis (fixation)
- Antibiotics in the case of infected nonunion
Complications due to immobilization
- Thrombosis, pulmonary embolism
- Infections (e.g., pneumonia, urinary tract infection)
We list the most important complications. The selection is not exhaustive.