Coxsackie viruses are a group of RNA viruses with over 20 serotypes; depending on specific viral characteristics, these serotypes are further divided into groups A and B. Infection is associated with a wide range of symptoms, which are dependent on the exact serotype. Hand, foot, and mouth disease (HFMD) and herpangina are commonly caused by group A coxsackie viruses, while pleurodynia and myocarditis are caused by group B coxsackie viruses. Both groups may cause viral meningitis, conjunctivitis, or pneumonia. Diagnostic procedures and treatment should be tailored to the specific disease manifestation.
- Worldwide distribution
- Occur in all age groups
- Highest incidence in infants and young children (< 10 years) 
Epidemiological data refers to the US, unless otherwise specified.
Coxsackie A 
- Hand, foot, and mouth disease
Coxsackie B 
- Dilated cardiomyopathy
- Characteristics: highly contagious
- Clinical features
- Treatment: symptomatic
- Prognosis: self‑limiting
Coxsackie A and B