Benign tumors of the endometrium
Last updated: January 7, 2021Summary
Endometrial hyperplasia
Endometrial polyps
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Definition: focal overgrowth of localized benign endometrial tissue
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Characteristics
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Epidemiology: prevalence rises with age (most common in postmenopausal women) [6]
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Risk factors
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Clinical features
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Diagnostics
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Treatment
- Asymptomatic women: observation and follow-up
- Symptomatic women: surgical removal
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Differential diagnosis
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Prognosis: ∼ 0.5–4% of uterine polyps are premalignant or malignant [7]
References
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G. Emons, M. W. Beckmann, D. Schmidt, P. Mallmann, and for the Uterus commission of the Gynecological Oncology Working Group (AGO). New WHO Classification of Endometrial Hyperplasias. Obstetrics and Gynecology. 2015
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Emad Rakha, Siew Chee Wong, Irshad Soomro, Zia Chaudry, Aarti Sharma, Suha Deen, Stephen Chan, Jafaru Abu, David Nunns, Karin Williamson, Angus McGregor, Robert Hammond, Laurence Brown. Clinical outcome of atypical endometrial hyperplasia diagnosed on an endometrial biopsy: institutional experience and review of literature. The American Journal of Surgical Pathology. 2012
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Wendy Wolfman. Asymptomatic Endometrial Thickening. Journal of Obstetrics and Gynaecology Canada. 2010
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- Lee-may Chen, Jonathan S Berek, Barbara Goff, S Dizon. Endometrial carcinoma: Clinical features, diagnosis, prognosis, and screening. In: Post TW, ed. UpToDate. Waltham, MA: UpToDate. https://www.uptodate.com/contents/endometrial-carcinoma-clinical-features-diagnosis-prognosis-and-screening.Last updated: November 1, 2019. Accessed: July 20, 2020.
- Reed SD, Urban RR. Management of Endometrial Hyperplasia. In: Post TW, ed. UpToDate. Waltham, MA: UpToDate. https://www.uptodate.com/contents/management-of-endometrial-hyperplasia.Last updated: November 29, 2017. Accessed: March 1, 2018.
- Elizabeth A Stewart. Endometrial polyps. In: Post TW, ed. UpToDate. Waltham, MA: UpToDate. https://www.uptodate.com/contents/endometrial-polyps.Last updated: May 25, 2020. Accessed: July 20, 2020.
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Stephanie L Wethington, Thomas J Herzog, William M Burke, Xuming Sun, Jodi P Lerner, Sharyn N Lewin, Jason D Wright. Risk and predictors of malignancy in women with endometrial polyps. Annals of Surgical Oncology. 2011
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Simple Typical Hyperplasia of Endometrium.
http://www.pathologyatlas.ro/simple-hyperplasia-endometrium.php.
Updated: January 30, 2009.
Accessed: March 1, 2018.
- Reed SD, Urban RR. Classification and Diagnosis of Endometrial Hyperplasia. In: Post TW, ed. UpToDate. Waltham, MA: UpToDate. https://www.uptodate.com/contents/classification-and-diagnosis-of-endometrial-hyperplasia.Last updated: April 27, 2017. Accessed: March 1, 2018.
- Wang Chiang J. Premalignant Lesions of the Endometrium. In: Huh WK, Premalignant Lesions of the Endometrium. New York, NY: WebMD. https://emedicine.medscape.com/article/269919. Updated: May 13, 2016. Accessed: March 1, 2018.
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Endometrial Hyperplasia.
https://radiopaedia.org/articles/endometrial-hyperplasia-1.
Updated: January 1, 2018.
Accessed: March 1, 2018.
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Sobczuk K. New classification system of endometrial hyperplasia WHO 2014 and its clinical implications. Menopause review. 2017
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